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Kavinace (120 count)

(1 customer review)

$88.00

Contains a blend of ingredients involved in the synthesis and activity of GABA, a neurotransmitter important for sleep*

Out of stock

SKU: 2079 Categories: , GTIN: 659468100748
Description

Description

Key ingredients:
GABA is the primary inhibitory neurotransmitter in the brain, meaning its central role is to balance excitability of neurons (1). Because of its function, GABA is important for promoting sleep, calm, and managing stress (2-4). Stress is thought to alter GABA synthesis and activity by affecting the expression of GABA-synthesizing enzymes and receptors (5).

Ingredients such as taurine and vitamin B6 are important for glutamate-GABA balance.* High glutamate can damage neurons, alter cellular homeostasis, and cause mitochondrial dysfunction, which can ultimately lead to cell death (6). Taurine demonstrates GABA-A agonist activity and protects neurons and mitochondria against glutamate-induced damage (6,7).* Active form of vitamin B6 is important for the synthesis of GABA as it is a required cofactor for glutamate decarboxylase, the enzyme responsible for converting glutamate to GABA (8-10).*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

References:
1. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.
2. Mohler H. Neuropharmacology. 2012;62(1):42-53.
3. Saper C, et al. Nature. 2005;437(7063):1257-63.
4. Mody I and Maguire J. Front Cell Neurosci. 2012;6:4.
5. Maguire J. Front Cell Neurosci. 2014;8:157.
6. Ye H, et al. Can J Neurol Sci. 2013;40(5):628-34.
7. Kletke O, et al. PLoS One. 2013;8(4):e61733.
8. Rowley N, et al. Neurochem Int. 2012;61(4):546-58.
9. Martin D. Cell Mol Neurobiol. 1987;7(3):237-53.
10. Mukherjee T, et al. Biochim Biophys Acta. 2011;1814(11):1585-96.

Additional information

Additional information

Weight 3 oz
Dimensions 24 × 1 × 2 in
Brand

NeuroScience

Form

Capsule

Department

Adult Health, Men’s Health, Women’s Health

Solutions

Anxiousness, Sleep, Stress

Neurotransmitter

GABA, Taurine

Reviews (1)

1 review for Kavinace (120 count)

  1. Stephanie Essig

    Kavinace works and works every night. I don’t think I can express how this has improved my life. just try it. The 120 ct bottle is better savings at $88.00 than the 60 ct bottle at $50.

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