Calm CP (60 count)

$58.00

Decreases cortisol levels and provides ingredients important for calm, sleep, and management of blood sugar.*

Supports a healthy response to stress.*

Calms anxiousness without causing sedating effects.*

SKU: 2099 Categories: , GTIN: 159468101115
Description

Description

Calm-CP

  • Banaba extract slows cortisol production
  • Phosphatidylserine supports responses to mental and physical stress

This product works well for supporting a healthy response to stress and reducing anxiousness without causing drowsiness or sedating effects.*

Key ingredients:
Lagerstroemia speciosa (Banaba) leaf extract (2% corosolic acid): Corosolic acid selectively inhibits 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1), an enzyme that catalyzes the conversion of cortisone into cortisol (1,2).* In a randomized study, corosolic acid was shown to significantly lower blood glucose levels by 20-30% after two weeks (3).*

Phosphatidylserine: Component of cell membranes important for receptor-mediated interactions (4).* Phosphatidylserine is thought to interact with cell membranes in order to dampen hypothalamic signaling and regulate the stress response (5).*

Glycine: Major inhibitory neurotransmitter that crosses the blood-brain barrier (6).* Binds receptors that regulate temperature during sleep (7).*

Taurine: Neuroprotective amino acid that provides antioxidant protection and demonstrates GABA-A agonist activity (8-10).* GABA is the primary inhibitory neurotransmitter in the brain important for calm and sleep (11-13).

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

References:
1. Rollinger J, et al. Bioorg Med Chem. 2010;18(4):1507-15.
2. Patel H, et al. Arabian Journal of Chemistry. 2015.
3. Judy W, et al. J Ethnopharmacol. 2003;87(1):115-7.
4. Monteleone P, et al. Eur J Clin Pharmacol. 1992;41:385-8.
5. Glade M and Smith K. Nutrition. 2015;31(6):781-6.
6. Kawai N, et al. Amino Acids. 2012;42(6):2129-37.
7. Kawai N, et al. Neuropsychopharmacology. 2015;40(6):1405-16.
8. Kumari N, et al. Adv Exp Med Biol. 2013;775:19-27.
9. Shimada K, et al. Adv Exp Med Biol. 2015;803:581-96.
10. Kletke O, et al. PLoS One. 2013;8(4):e61733.
11. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.
12. Mohler H. Neuropharmacology. 2012;62(1):42-53.
13. Saper C, et al. Nature. 2005;437(7063):1257-63.

Additional information

Additional information

Weight 3 oz
Dimensions 24 × 1 × 2 in
Brand

NeuroScience

Department

Adult Health, Men’s Health, Women’s Health

Form

Capsule

Hormone

Cortisol

Neurotransmitter

Glycine, Taurine

Solutions

Adrenal, Immune, Sleep, Weight Management

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